
Trusted Clinical Genomics Infrastructure
Smart Genome combines clinical whole genome reporting, genomic interpretation, and large-scale genome exploration in a unified platform for healthcare, research, and precision medicine.
Built on years of clinical reporting experience and validated genomic methodologies, Simplify Genomics helps organizations transform genomic data into clinically meaningful insights and actionable knowledge.
Clinical Genomics Intelligence
Simplify Genomics combines clinical reporting expertise, curated genomic knowledge, and scalable genome intelligence infrastructure to support healthcare, research, and precision medicine programs.
- CLIA-certified and CAP-accredited genomic reporting
- Clinical Whole Genome reporting since 2018
- Hereditary Disease, Polygenic Risk, and pharmacogenomics reporting
- Clinical Decision Support with Genetic Counselor services


Featured Resources
- Polygenic Risk Score Validation: How We Evaluate Genetic Risk ModelsPolygenic Risk Scores (PRS) have emerged as one of the most promising tools in genomic medicine, offering insights into an individual’s inherited predisposition to common complex diseases. By combining the effects of thousands—or even millions—of genetic variants across the genome, PRS models can help estimate relative disease risk beyond traditional family history alone. However, not… Read More »Polygenic Risk Score Validation: How We Evaluate Genetic Risk Models
- “Clinical Grade” Sequencing Isn’t the Gold StandardWhat Consumers Should Know About Genomic Testing In this article, Wayne Delport challenges the common assumption that “clinical-grade sequencing” automatically represents the highest standard in genomic testing. The piece explores the technical, analytical, and regulatory differences between clinical sequencing pipelines and modern high-resolution consumer genomics platforms, highlighting how the term “clinical-grade” is often used inconsistently… Read More »“Clinical Grade” Sequencing Isn’t the Gold Standard
Genomic Findings
Learn how the Smart GenomeTM platform unifies genomic information in one platform and how our approach can be applied to transform patient care in your organization.


1.6M+ variants interpreted

2000+ genes and 2100+ hereditary disease associations curated

5+ years CLIA-certified and CAP-accredited Whole Genome Sequence reporting

~1.5 Billion queryable variant records

Let’s discuss your needs
We can provision your genomic data in a fast, queryable, secure platform