
Trusted Clinical Genomics Infrastructure
Smart Genome combines clinical whole genome reporting, genomic interpretation, and large-scale genome exploration in a unified platform for healthcare, research, and precision medicine.
Built on years of clinical reporting experience and validated genomic methodologies, Simplify Genomics helps organizations transform genomic data into clinically meaningful insights and actionable knowledge.
Clinical Genomics Intelligence
Simplify Genomics combines clinical reporting expertise, curated genomic knowledge, and scalable genome intelligence infrastructure to support healthcare, research, and precision medicine programs.
- CLIA-certified and CAP-accredited genomic reporting
- Clinical Whole Genome reporting since 2018
- Hereditary Disease, Polygenic Risk, and pharmacogenomics reporting
- Clinical Decision Support with Genetic Counselor services


Featured Resources
- Rethinking Clinical Actionability in GenomicsOne question frequently asked is: “How many actionable genes do you report?” While this sounds like a simple question, it is really asking something much broader: “Under what circumstances can genomic information inform patient care?” The true value of genomic testing is not measured by the number of genes labeled as actionable. Instead, it depends on whether a… Read More »Rethinking Clinical Actionability in Genomics
- AI Democratizes the Appearance of Expertise. In Genomics, That’s a ProblemArtificial intelligence is rapidly transforming genomics, making powerful analytical tools accessible to more people than ever before. But while AI can generate convincing interpretations, it does not replace the deep expertise required to evaluate genetic evidence, recognize uncertainty, and make clinically defensible decisions. In this article, Wayne Delport explores why genetic interpretation is fundamentally different… Read More »AI Democratizes the Appearance of Expertise. In Genomics, That’s a Problem
Genomic Findings
Learn how the Smart GenomeTM platform unifies genomic information in one platform and how our approach can be applied to transform patient care in your organization.


1.6M+ variants interpreted

2000+ genes and 2100+ hereditary disease associations curated

8+ years CLIA-certified and CAP-accredited Whole Genome Sequence reporting

~1.5 Billion queryable variant records

Let’s discuss your needs
We can provision your genomic data in a fast, queryable, secure platform