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Your genome. A deeper understanding of your health.

Your Genome
Why Simplify?
Why WGS?
What You Get
How it Works
FAQ

Trusted by healthcare providers. Now accessible to you.

Built on years of experience supporting physicians, concierge medical practices, and longevity clinics, Simplify Genomics now offers our Whole Genome Sequencing (WGS) Screening test to individuals seeking deeper understanding of their genetic health through a healthcare provider-authorized process.

Our CLIA-certified, CAP-accredited clinical laboratory provides comprehensive genomic reports with insights into inherited health risks, how your genetics may influence medication response, polygenic risk scores, and health and wellness traits—helping you and your healthcare provider make more informed decisions about your genetic health.

Whole genome sequencing requires review and authorization by a qualified, licensed healthcare provider. Submitting your registration does not constitute a laboratory test order or guarantee authorization for testing. If your test is not authorized, your payment will be fully refunded to your original payment method.

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View Pricing – $950

What can your genome reveal?

Meaningful genetic insights. Grounded in scientific evidence.

Your genome holds valuable information about your genetic health—from inherited disease risks to how your body may respond to medications. Simplify Genomics translates this complex genetic information into meaningful insights through clinical genomic analysis, evidence-based interpretation, and qualified clinical review.

Because when it comes to your health, the quality and reliability of your results matter.

Our CLIA-certified, CAP-accredited clinical laboratory performs genomic analysis, interpretation, and reporting using validated methods, established quality standards, and review by qualified clinical laboratory personnel.

Inherited Health Risks

Identify selected genetic variants associated with inherited conditions and health risks, including certain hereditary cancers, cardiovascular disorders, and neurological diseases.

Medication Response and Safety

Learn how your genetics may influence your response to certain medications. Our pharmacogenomics reporting covers medications across a wide range of therapeutic areas, including cardiovascular health, pain management, and mental health. These insights can help inform discussions with your healthcare provider about medication selection, dosing, and potential adverse effects.

Polygenic Risk

Your risk for many common conditions is influenced by thousands of genetic variants working together. Polygenic risk scores help assess inherited susceptibility to conditions such as coronary artery disease, breast cancer, type 2 diabetes, and Alzheimer’s disease—providing additional context for personalized preventive care. Polygenic risk scores provide additional information about genetic predisposition and can be considered alongside your personal and family health history.

Health and Wellness Insights

Explore selected genetic traits associated with nutrition, physical characteristics, and other aspects of health and wellness. These insights may provide additional context for understanding your individual characteristics and discussing lifestyle and wellness considerations with your healthcare provider.

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Why Simplify Genomics?

Beyond sequencing. The science of understanding your genome.

Understanding what your genomic information means for your health requires more than sequencing alone. At Simplify Genomics, we combine years of clinical genomics experience, advanced technology, and scientific expertise to provide meaningful genetic information that you and your healthcare provider can use.

Proven Clinical Experience

Trusted by physicians. Built on years of clinical experience.

Our technology builds on more than eight years of experience in clinical whole genome analysis, interpretation, and reporting. Since 2018, our team and technology have supported healthcare providers, concierge medical practices, and longevity clinics with comprehensive clinical genomic reports, helping inform personalized patient care.

Clinical Quality & Scientific Rigor

Clinical laboratory testing. Beyond software-generated insights.

At Simplify Genomics, genomic analysis, interpretation, and reporting are performed within our CLIA-certified, CAP-accredited clinical laboratory—not simply generated through a consumer-facing software platform. These processes incorporate validated methods, established quality controls, and review by qualified clinical laboratory personnel.

Advanced Genomic Expertise

Advanced technology. Expert interpretation.

Our advanced analysis and interpretation processes draw on curated genomic databases, published scientific evidence, and recognized clinical guidelines. Genetic findings undergo qualified clinical review to provide evidence-based interpretations that go beyond automated variant identification.

Privacy & Security

Your genome is personal. Your privacy matters.

Your genome is personal, and protecting your information is a priority. We use administrative, technical, and physical safeguards designed to protect your genetic and health information throughout the testing and reporting process. Learn more in our Notice of Privacy Practices.

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Why whole genome sequencing?

A broader view of your genetic health.

Your DNA contains valuable information about your health, but not all genetic tests examine the same amount of information. Your genome contains approximately 3.2 billion DNA positions. While many genetic tests examine specific genes or selected genetic variants, whole genome sequencing takes a broader approach by examining DNA across the genome—providing a more comprehensive foundation for understanding your genetic health.

Sequencing is only the beginning.

Having your DNA sequenced is one thing. Understanding what it means is another. Whole genome sequencing provides extensive genetic information that can be analyzed and interpreted to identify findings relevant to your genetic health.

Your genome doesn’t change, but our understanding of it does.

As scientific knowledge advances, new relationships between genetic variants and health continue to emerge. Whole genome sequencing provides a broad foundation that may support additional insights if your genomic data is reanalyzed or reinterpreted in the future.

Understanding Healthy Screening

Simplify Genomics’ WGS Healthy Screening test is intended to identify selected genetic findings associated with inherited conditions and health risks. It is not intended to diagnose an existing medical condition or replace diagnostic genetic testing when clinically indicated. Certain findings may warrant additional medical evaluation or confirmatory testing.

Whole genome screening does not detect all genetic variants or health conditions. A negative result does not eliminate the possibility of a genetic condition or future health risk. Results should be interpreted in the context of your personal and family health history and discussed with a qualified healthcare provider.

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What should you look for in a genetic test?

If you want to use your genetic results in your healthcare, not all testing services are the same.

Before choosing a genomic testing service, consider these five important questions.

1. Can the results be used in your medical care?

Understand whether the service provides informational genetic insights or a clinical laboratory report intended to support medical care. Results from direct-to-consumer genetic testing may require additional clinical testing or confirmation before they can guide healthcare decisions. 

How Simplify delivers

Our whole genome screening results are provided in a clinical laboratory report designed to support informed discussions and healthcare decisions with your provider.

2. Are both sequencing and genomic analysis performed under clinical laboratory standards?

Clinical genomic testing involves more than generating DNA sequence data. Both sequencing and downstream genomic analysis must be appropriately validated and performed within a clinical laboratory quality framework for the intended clinical use. Having DNA sequenced by a CLIA-certified laboratory does not automatically mean that the analysis and interpretation performed by a separate software service is clinical laboratory testing.

How Simplify delivers

Our sequencing is performed under applicable clinical laboratory quality standards, while genomic analysis and interpretation are conducted within our CAP-accredited, CLIA-certified clinical laboratory.

3. How are genetic findings interpreted and reviewed?

Genomic analysis often involves sophisticated algorithms and automated tools. For clinical reporting, these processes should be validated, supported by scientific evidence, and subject to appropriate oversight and review by qualified clinical laboratory personnel. Understanding who is responsible for interpreting and authorizing your results is essential.

How Simplify delivers

Our genomic analysis uses validated methods and evidence-based interpretation, with clinical oversight and final report authorization by qualified clinical laboratory professionals.

4. How much of your DNA is examined—and how reliably?

Genetic tests differ in the regions examined, sequencing depth, and ability to detect certain types of variants. Broader coverage provides more genomic information but does not guarantee that every variant can be reliably identified or interpreted.

How Simplify delivers

We use high-coverage whole genome sequencing, supported by rigorous quality controls and validated analytical methods, to examine nearly your entire genome and identify clinically relevant genetic findings.

5. Is a healthcare provider involved?

Find out who determines whether testing is appropriate, who authorizes the test, and how results are reviewed with you. A qualified healthcare provider can help interpret findings in the context of your personal and family health history and determine whether additional evaluation is appropriate.

How Simplify delivers

Every test is authorized by an independent licensed healthcare provider, with post-test genetic counseling that includes a personalized results summary and a consultation with a genetic counselor.

The right genetic test depends on your health goals and how you intend to use the results. If you want results to inform your medical care, look for a service that combines appropriate clinical laboratory testing, validated genomic analysis, qualified interpretation, and healthcare provider involvement.

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How it works

Your journey to better understanding your genetic health.

From test registration to receiving your results, we’ve designed a straightforward process that includes healthcare provider authorization, convenient at-home sample collection, and access to your clinical genomic report.

1. Register and Request Testing

Create an account in our secure patient portal, provide your health information, and review and sign the genetic testing consent. A qualified, licensed healthcare provider will review your information to determine whether testing is appropriate. If authorized, your test order will be submitted for processing.

2. Collect Your Sample

Once your test is authorized, we’ll send a saliva specimen collection kit directly to you. Follow the included instructions to collect your sample at home and return it using the prepaid shipping materials provided.

3. We Sequence and Interpret Your Genome

Your sample is sequenced by our CLIA-certified, CAP-accredited reference laboratory. Simplify Genomics then performs clinical genomic analysis, interpretation, and reporting within our own CLIA-certified, CAP-accredited laboratory.

4. Receive and Understand Your Results

When your results are ready, you’ll be notified and can securely access your clinical genomic report through the patient portal. Your test includes a 30-minute genetic counseling appointment to help you understand your findings and discuss next steps.

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SIMPLE, TRANSPARENT PRICING

One Test. A Broader View of Your Health.

$950

One-time payment. No subscription.

✅ Whole-genome sequencing, comprehensive genomic analysis, clinical interpretation, and personalized reporting of your genetic health insights. For an example report, please click here.

✅ An easy-to-use saliva collection kit delivered to your home, including prepaid return shipping.

✅ An independent, licensed healthcare provider reviews your test request, determines your eligibility, and authorizes testing when appropriate.

✅ A personalized written summary of your genomic screening results prepared by an independent genetic counseling service.

✅ A 30-minute consultation with an independent genetic counselor after your results are available to help you understand your findings, ask questions, and discuss potential next steps.

Ordering available soon

Questions? Contact our team to learn more.

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Frequently Asked Questions

About the Test

Whole genome sequencing (WGS) examines DNA across the genome, providing a broader view of genetic information than tests focused on selected genes or variants. Results may identify genetic findings relevant to your health.
Your clinical genomic report provides information about selected inherited health risks, medication-response associations, polygenic risk scores, and health and wellness traits. The findings included depend on the scope of the test and the genetic variants identified.
No. Whole genome screening is intended to identify potential genetic health risks in individuals who may not have symptoms. It is not intended to diagnose a medical condition or replace diagnostic testing recommended by your healthcare provider. Some findings may require additional evaluation or confirmatory testing.
Not necessarily. Genetics is only one factor influencing your health. Lifestyle, environment, medical history, and other factors also play important roles. Some genetic variants are associated with substantially increased disease risk, while others have smaller effects. Your results should be considered alongside your personal and family health history.
The WGS Healthy Screening test costs $950 and includes independent healthcare provider review, whole genome sequencing, clinical genomic analysis and reporting, a saliva collection kit with prepaid return shipping, and one 30-minute genetic counseling appointment. A personalized written summary is provided following the counseling appointment.
Simplify Genomics' WGS Healthy Screening test is currently self-pay. We do not bill health insurance for this service.

Registration & Eligibility

Yes. Testing requires an order from a qualified, licensed healthcare provider authorized to order the test. You can initiate a request through our patient portal, but testing will not proceed until an independent telehealth provider reviews and authorizes it.
If the reviewing healthcare provider determines that testing is not appropriate or does not authorize your request, your test will not be ordered and your payment will be fully refunded to your original payment method.
Yes. You can initiate registration without an order from your personal physician. An independent, licensed healthcare provider will review your request and authorize testing if appropriate.
Most people are eligible for whole genome screening, with a few exceptions: those who have received a bone marrow transplant, a blood transfusion in the past three weeks, or a stem cell treatment from a donor in the past three weeks or currently pregnant. Specimens collected in New York cannot be accepted at this time. Note that eligibility and approval for testing are ultimately determined by a qualified health provider.
No, at this time testing is only available within the United States.

Sample Collection & Testing

Once your test is authorized and Simplify Genomics receives the test order, a saliva sample collection kit will be shipped to your provided address. The collection kit includes instructions for collecting your sample at home and returning it to our laboratory using the prepaid shipping label provided.
Whole genome sequencing involves several stages, including sample processing, sequencing, quality assessment, genomic interpretation, and clinical review. We typically have results available within 6 weeks after we receive your sample.

Results & Privacy

Once your results are available, we'll notify you and provide secure access to your clinical genomic report in the Patient Portal. Your report presents your genetic findings in an organized format designed to support review and discussion with a qualified healthcare professional.
Your results are intended to be reviewed with a qualified healthcare provider or genetic counselor, who can help explain their significance and discuss whether any follow-up is appropriate. A 30-minute genetic counseling appointment is included with your test purchase.
Yes. Simplify Genomics provides clinical genomic reports intended to support discussions with your healthcare provider. Whole genome sequencing is performed through a CLIA-certified, CAP-accredited reference laboratory, while genomic analysis, interpretation, and reporting are performed by Simplify Genomics within our CLIA-certified, CAP-accredited clinical laboratory. Your healthcare provider can review the findings alongside your medical and family history to determine whether additional evaluation or confirmatory testing is appropriate.
Simplify Genomics treats your genomic information as sensitive health information. We use security and privacy safeguards, including access controls and secure systems, designed to protect your information throughout testing, analysis, storage, and reporting. We are a covered entity under HIPAA and follow all HIPAA privacy and security guidelines.
If you would like to discuss your results with a genetic counselor, we provide a free 30-minute consultation. We use an external service for genetic counseling, and you can schedule additional appointments with them at your own expense.
Your DNA sequence remains largely unchanged throughout your life, but scientific understanding of genetics continues to advance. Whole genome sequencing provides a broad foundation of genomic information that may support additional interpretation as new scientific knowledge becomes available. Future analyses or updated reports may require additional services.
Yes, the report typically includes all information considered reportable when we generate it. However, as the field continues to evolve, new information may become available that was not included in your original report. We can generate a new report based on updated information without resequencing your genome. Please contact us if you are interested. We can also provide raw data upon request. This will be available in the patient portal where you have registered.
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Further Questions

If you have any questions, please contact us via our Patient Inquiry Form.